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Automated
Blood Grouping
Ortho Autovue Blood Grouping System brings automation to the WPBTS
Blood Banks
The WPBTS after a period of testing and evaluation have purchased
the Ortho Autovue system. This new system will see for the first time
in the WPBTS the automation of the blood grouping process. The evaluation
period of this new system started in July 2005 and was conducted at
Tygerberg Hospital. The medical staff and superintendent of Tygerberg
Hospital greatly assisted in the evaluation of this new technology.
The evaluation period ended in October 2005 and focused on the following
areas:
- Subgroups
- Antibody titres
- Weak examples of D antigen
- Problem groups
- Antibody screens (clinically significant, as well as
insignificant)
The analyzer produced consistent results in comparison with our manual
crossmatch method. The system is very sensitive and for example, found
Direct Coombs tests positive where the manual method produced a negative
result. The positive result is due to the fact that the majority of
the patient population is on some form of drug treatment.
Advantages of the system
- Decreased hands-on time, which reduces the possibility
of operator error.
- Improved quality in terms of consistency of results
and techniques.
- Increased productivity - random access, batch, STAT
and continuous feed modes; consumables are monitored continuously
(reagents & cassettes); liquid level detection ;for
samples and reagents; intuitive menu - driven computer screens.
- Safety - fully enclosed system; software controlled
access doors; minimal handling of patient samples; automated
cassette disposal.
- System / data security - positive sample and reagent
identification; positive cassette identification; automated
reading, reaction grading and interpretation of results;
password protected; bi-directional interface.
- Consistent, high quality results - standardized pipetting,
incubation, centrifugation and reading / interpretation;
positive sample, reagent and cassette ID.
Turnaround time
The turnaround time is expected to be 1 hour from receipt at blood
bank to completion. The current time for a standard crossmatch / group
& screen is 1 hour and 30 minutes. This is due to a decrease in incubation
time (from 30 minutes manually to 15 minutes on Autovue) and because
all aspects of testing are standardised and automated on the Autovue.
Distribution of analysers
Groote Schuur and Tygerberg blood banks each have one Autovue (fully
automated) and one Biovue (semi-automated). The Autovue analyzer will
be used for routine testing and the Biovue as a 'back-up' or for problem
samples.
Medicity Vergelegen blood bank will have one Biovue system and Red
Cross Hospital blood bank will have 2 Biovue systems. It is currently
the plan to automate Paarl, Worcester and George in the next financial
year.

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